Angong Niuhuang Pills contains three kinds of in vitro cultivated oxalis, artificial musk and ice tablet to open the orifices. Angong Niuhuang Pill is mainly composed of in vitro cultivated ox-huang, artificial musk, andrographis, scutellaria baicalensis, icicle, vermilion sand and other traditional Chinese medicines, of which three kinds of traditional Chinese medicines, namely, in vitro cultivated ox-huang, artificial musk and icicle, have the efficacy of opening up the orifices. This medicine has the efficacy of suppressing alarm and opening the orifices, clearing heat and removing toxins (removing heat and toxicity and evil qi from the body), and can be used for the treatment of febrile diseases, febrile convulsions (convulsions and convulsions due to high fever), delirium tremens (delirium with confused consciousness, babbling nonsense), and evil entering the pericardium; and those who are in coma after stroke, meningitis, septicemia, cerebral hemorrhage, and toxic encephalopathy with the above mentioned signs and symptoms. The adverse reactions and contraindications of Angong Niuhuang Wan are not clear, athletes and pregnant women should be cautious. This drug needs to be taken under the guidance of traditional Chinese medicine diagnosis, and should not be taken blindly on its own, so as not to cause damage.