Normal aminotransferase and high bilirubin may be caused by liver disease, biliary tract disease, vascular disease or physiological factors. 1. Liver diseases: such as liver fibrosis, cirrhosis, and intrahepatic bile ducts damage, may lead to bile metabolism is affected, usually for the bile ducts damage is more obvious, for the hepatocyte damage is not serious, so aminotransferases are usually normal. 2. Biliary tract diseases: such as gallstones, cholecystitis, gallbladder surgery and extrahepatic bile duct obstruction, may cause. 3. Blood diseases: if the blood vessels have symptoms of hemolysis, hemolytic jaundice will be induced, which may also cause elevated bilirubin and normal transaminases at the same time. 4. Physiological factors: Irregular diet, prolonged late night, overwork, obesity can cause bilirubin elevation and normal aminotransferase. It is suggested that patients need to go to the regular hospital to receive further examination, according to the results, under the guidance of specialized doctors.