In clinic or online, questions are often asked about women testing themselves as soon as their period is over, or going to the hospital to check if they are pregnant with a blood draw and ultrasound. When they arrive at the hospital, the doctor has to prescribe tests, such as ultrasound, blood or urine tests, to confirm whether they are pregnant or not. The results of these tests are often confusing: the ultrasound does not show a gestational sac or a pulsating heart tube; the blood test shows “low progesterone”. Patients ask if they will miscarry. Is it possible to keep the pregnancy? It is important to consider this in the context of gestational age or menstrual cycle, and requires dynamic observation and review for comprehensive analysis and consideration. Many pregnant women ask or their doctors prescribe birth control pills or injections when they have a small amount of bleeding or “low progesterone”. The progesterone secreted by the body fluctuates greatly and is metabolized quickly, so the test results are unstable. Progesterone is the easiest and safest way to give it to a pregnant woman (if it is not prescribed, the pregnant woman will look for her doctor after the miscarriage because she was not given a birth control), but it is mostly used as a placebo. If the pregnant woman’s own secretion is not enough, “hormonal birth control” is to use hormones to promote the growth and development of the embryo, is to supplement the pregnant woman’s own hormone secretion deficiency with exogenous hormones, birth control drugs will work. If the embryo is abnormal (Down’s or other chromosomal abnormalities), the embryo will not produce enough hormones, and if large doses of exogenous hormones are used to protect the fetus, the result is that the embryo that should have been aborted survives. If not hormone deficiency, too much hormone will only cause adverse effects to the fetus and the pregnant woman. Bleeding in early pregnancy is relatively common, and most of it is caused by abnormal embryos or other causes, with abnormal hormone levels accounting for only a small percentage. It is the cause of the bleeding that should be carefully examined and the adverse consequences of the pregnancy that should be considered. After pregnancy, HCG is secreted during the development of the chorionic villi, including the yolk sac and the placenta. If the HCG growth is normal, it indirectly indicates that the embryo is developing normally, and if there is a miscarriage it is not due to hormonal insufficiency, but must be due to other causes (hormonal insufficiency is one of the many causes of miscarriage). Due to the instability of progesterone and the different methods of examination, there will be deviations in the test results. Using a combined progesterone and HCG test, if only the progesterone is low and the HCG is normal, it is most likely an error in the test and should be rechecked or the HCG result should be the main factor, and should also be combined with the patient’s menstrual condition. It should be combined with gestational age, HCG, ultrasound and other comprehensive and integrated analysis, rather than looking at a particular result as the basis for treatment.