Depending on the cause and the degree of the patient’s condition, the labia majora and minora should be separated by medication, such as estrogen ointment, or by surgery, as prescribed by the doctor. Closure of the labia majora and minora is easily caused in infancy and old age. In infancy and early childhood, due to improper care by family members, urethral, vaginal and anal secretions are not cleaned up in time, which may cause localized inflammation of the labia. If not treated in time, it will gradually cause labia adhesion closure. Ageing labia majora and minora closure is often caused by vulvar lesions, such as vulvar white lesions caused vulvar atrophy, erosion, the formation of adhesions, closure. If detected at an early stage, you can follow the doctor’s instructions to apply local anti-adhesion ointment, such as estrogen ointment, and keep the vulva clean and dry, and change underwear frequently. In severe cases, surgery is needed to separate the adhesions. Patients with labia major and minor are closed, it is recommended to consult a doctor in a timely manner, complete the relevant examination, under the guidance of a professional doctor to determine the cause of the disease, targeted treatment. The use of drugs need to follow the doctor’s instructions.