During pregnancy, changes in hormone levels during pregnancy can cause conditions such as gingival hypertrophy, which can predispose to gingivitis and result in bleeding gums, especially after brushing teeth, a common symptom in late pregnancy. Gingivitis is also a common cause of gum hypertrophy. Gingivitis is an inflammation of the gums, often accompanied by grinding of the teeth and bleeding gums. The laboratory tests for gingival hypertrophy due to gingivitis must be summarized and analyzed on the basis of the objective material learned from the medical history and physical examination, from which several diagnostic possibilities are suggested, and then further consideration is given to which laboratory tests are done to confirm the diagnosis. Gingival hypertrophy due to gingivitis can be examined by oral examination, which shows bleeding, redness, swelling and pain of the gums, increased amount and temperature of the gingival sulcus; oral X-ray examination and oral consultation. The examination of gingival hypertrophy caused by gingivitis: 1. Blood test: High white blood cell count above 100×109/L, mostly neutrophilic rod nuclei and late juvenile granulocytes in blood film, the rest are foliated nuclei, medium juvenile granules, early juvenile granules and a few primitive granulocytes. Eosinophilic and basophilic granulocytes were also increased. In the early stage, hemoglobin and red blood cells were mildly decreased, platelets were normal or increased, and in the late stage, red blood cells and platelets were decreased. Ph’ chromosome is considered to be a tumorigenic marker of pluripotent stem cells, but a small number of patients with slow granules are negative for Ph’ chromosome. Ph’-positive and Ph’-negative, the former has better prognosis than the latter. 3, blood biochemical examination: serum vitamin B12 concentration and vitamin B12 binding power significantly increased as one of the characteristics of the disease, the magnitude of the increase is proportional to the degree of leukocytosis.