Normally, patients can return to normal after 3~5 days of blood transfusion. However, for those caused by severe primary diseases, such as leukemic anemia, if the disease is not in remission, it is difficult to return the blood routine to normal through blood transfusion treatment alone. 1. Usually, when severe anemia or very severe anemia occurs, the hemoglobin concentration is lower than 60g/L, and the patient has obvious clinical symptoms, blood transfusion treatment is needed. With blood transfusion therapy, the patient’s hemoglobin value can usually be restored to a reasonable value after 3 to 5 days. The so-called reasonable value usually does not mean that the patient’s hemoglobin concentration has completely returned to normal, but means that the patient’s hemoglobin has recovered to more than 80g/L and the patient has no obvious clinical symptoms. In addition, because blood transfusion does not completely cure anemia, it is usually used to relieve emergency symptoms caused by severe anemia. 2. When the patient’s anemia is caused by primary diseases, such as acute leukemia, aplastic anemia, myelodysplastic syndrome, severe liver disease, hemolytic anemia, etc., and if the treatment of the primary disease is ineffective and the condition continues to progress, blood transfusion alone cannot restore the blood routine results to normal. Therefore, if you want your anemia patient’s hemoglobin concentration to return to normal, it is recommended that you go to the hospital for a systematic examination. Only when the cause of the disease is identified and targeted treatment of the primary disease is carried out under the guidance of the physician can the indexes return to normal.