Primary thrombocytopenia is an autoimmune disease in which the body produces autoantibodies against platelets, resulting in excessive destruction of platelets in the blood circulation and a series of bleeding symptoms. The treatment of primary thrombocytopenia is divided into general treatment and symptomatic treatment. The general treatment is to keep the patient in bed, pay attention to rest, do not eat anything too hard, and apply hemostatic drugs to treat the bleeding, and if there is serious bleeding, platelet transfusion treatment. The most common symptomatic treatment is glucocorticoid therapy, because glucocorticoids can reduce the production of autoantibodies, improve capillary permeability, and stimulate the release of platelets into the peripheral blood. Commonly used drugs include prednisone acetate, dexamethasone, etc. If hormone therapy does not work, spleen excision can also be given. Targeted drugs, such as melphalan, can also be used; TPO receptor agonists can also be used to promote platelet release.