Co-medication in bile reflux gastritis is usually a combination of pro-gastrointestinal dynamics drugs, gastric mucosal protectants, and acid inhibitors. Bile reflux gastritis is an inflammation of the gastric mucosa caused by the reflux of bile-containing duodenal contents into the stomach. Treatment is based on drugs, and the combined use of multiple types of drugs can improve the efficacy. Gastrointestinal stimulating drugs can promote gastric emptying and reduce bile secretion, commonly used are domperidone, cisapride and so on. Gastric mucosal protective agent can avoid the erosion of gastric mucosa by bile acid and gastric acid, commonly used are bismuth potassium citrate, aluminum thiosulfate and so on. Acid inhibitors can inhibit gastric acid secretion, commonly used are omeprazole, lansoprazole and so on. Bile can also be adsorbed with ursodeoxycholic acid. The specific medication varies, and it is recommended to consult a doctor in time and follow the doctor’s instructions.