Currently, new coronavirus infection pneumonia is prevalent in the country. Because of the strong contagiousness and insidious onset, hospitals at all levels may become potential infection centers, and many patients are unable to go to hospitals, which seriously affects the consultation and treatment of oncology patients. New coronavirus pneumonia has symptoms such as fever, malaise and dry cough, mainly with lung lesions, and severe patients have respiratory difficulties and even respiratory failure. China has designated novel coronavirus infection pneumonia as a statutory infectious disease, according to the official announcement of three routes of infection: respiratory droplet transmission, contact transmission, aerosol transmission, Zhong Nanshan academician in a newly published paper proposed not to exclude fecal-oral transmission. Controlling the source of infection, cutting off the transmission route, and protecting the susceptible population are important measures to reduce the new coronavirus infection pneumonia. Oncology patients are in a special immune state due to the disease itself, surgery, radiotherapy treatment, and are susceptible to novel coronavirus, and are more likely to develop novel coronavirus infection than normal people. In view of the special population of oncology patients, the potential risk of hospital visits and limited medical resources, we will discuss the prevention of infection in oncology patients during the epidemic of neocoronavirus pneumonia. We hope to ensure the safety and efficacy of oncology patients through scientific prevention and control, standardized diagnosis and treatment for the reference of oncology patients and their families. I. Oncology patients with fever symptoms Oncology patients with fever within 72 hours are recommended to go to the fever clinic of local general hospital for consultation and investigation. After confirmed as suspected cases meeting the definition of cases, they should be immediately isolated and treated in designated hospitals with effective isolation and protection conditions. For patients with common fever who are clearly excluded from the new coronavirus infection, it is recommended to communicate with the previous supervising physician in a timely manner, explain the condition and symptoms, and provide symptomatic treatment under the guidance of experienced oncologists. For patients with fever and infection due to the decrease of immune status after anti-tumor treatment such as radiotherapy and chemotherapy, it is recommended to carry out systematic and comprehensive treatment after multidisciplinary consultation of oncology specialists and infection departments. If it is true that the original disease is aggravated, patients can be hospitalized in a general hospital for oncology treatment. For patients with benign tumors that do not affect their health in the near future and patients in remission of malignant tumors after comprehensive treatment, it is recommended to moderately postpone surgical treatment. For patients with progressive malignant tumors, surgery should be carried out under controlled risk conditions after a comprehensive and detailed assessment of the patients’ physical status and surgical risks. For patients with critical malignant tumors or serious complications of malignant tumors requiring emergency surgery, surgical treatment should be carried out under the premise of fully assessing the immune status of patients and fully ensuring the safety of postoperative adjuvant therapy, and it is recommended to strengthen the protection against infectious diseases during treatment to ensure the perioperative safety of patients. III. Patients with tumors to be treated with chemotherapy For malignant tumors with normal physical status, systemic chemotherapy should be carried out after detailed assessment of chemotherapy risk again, while avoiding low immune status after chemotherapy. For elderly and frail tumor patients with multiple lines or multiple courses of chemotherapy and poor immune status, it is recommended to carry out chemotherapy after enhancing immune capacity to normal state, and the dose of chemotherapy drugs can be moderately reduced and/or chemotherapy cycles can be extended without significantly affecting the efficacy. For patients with postoperative adjuvant chemotherapy or chemotherapy in remission of tumor, it is recommended to moderately delay chemotherapy under the premise of ensuring that it does not affect the prognosis of tumor. IV. Patients with tumor review For patients with routine review of malignant tumors, it is recommended to delay the review without affecting the prognosis of the disease; simplify the review procedures and means as much as possible during the review process to reduce the time in the hospital. For tumor patients with stable post-operative conditions who need long-term oral Chinese medicine for maintenance or conditioning purposes, the basic premise of Chinese medicine is to consider the evidence-based administration of Chinese medicine, and if there is no change in symptoms and stable conditions after taking the medicine, the prescription of Chinese medicine may not be changed, and this time should not exceed 3 months at most, and monthly adjustment is recommended if available. Other patients need to decide how to take Chinese medicine after consulting with an experienced Chinese medicine practitioner according to their treatment condition. Diet advice for tumor patients should ensure adequate nutrition, daily intake of high-protein food, appropriate supplementation of fresh fruits and vegetables to achieve a balanced diet; drink an appropriate amount of water, not less than 1500ml per day; regular rest and sleep; and physical exercise according to individual conditions. Seven, how to seek medical treatment for tumor patients It is recommended that patients should seek medical treatment near to their home because of their diseases, so as to reduce long distance travel and cross-infection opportunities. In particular, patients should avoid cross-city and cross-province medical consultations; try to take private cars or cabs, and avoid taking trains and subways for crowded transportation. Avoid coughing, talking and sneezing; avoid staying in shopping, dining and entertainment places; pay attention to personal hygiene, wear disposable gloves, wash hands regularly and use alcohol-based hand sanitizer if possible; pay attention to protecting the health and safety of people around you, do not spit, and do not throw away discarded masks. Finally, remind the majority of patients and their families, if there are no special circumstances, it is recommended to stay at home to rest or network for medical consultation, the hospital may also not be the safest place.