According to the Chinese Pharmacopoeia, the dosage of Huanglian decoction is 2~5g, so the dosage of Huanglian 12g is on the high side. Huanglian is bitter and cold in nature, it can clear heat and dry dampness (removing heat and drying dampness), and is widely used in damp-heat cases. Because of its main entry into the middle Jiao, it is good at removing dampness and heat in the spleen and stomach (the spleen and stomach feel dampness and heat), so it is mostly used in the middle Jiao dampness and heat syndrome. This product is often paired with Houpu, gardenia, calamus, etc., used for the treatment of damp-heat accumulation (dampness and heat in the body gathered each other) caused by the middle jiao of the chest and epigastric plagiarism, vomiting, diarrhea and so on. Huang Lian is good at clearing fire in the heart and stomach, so it can be used in cases of heart fire and stomach fire. This product also has a good effect of diarrhea and detoxification (elimination of fire and toxicity in the body), and is suitable for sores, carbuncles and swollen toxins with redness, swelling, heat and pain. According to the Chinese Pharmacopoeia, the dosage of Rhizoma Coptidis decoction is 2~5g, so the dosage of Rhizoma Coptidis 12g is too much. For the sake of medication safety, it is recommended to refer to the Chinese Pharmacopoeia for the dosage. Huanglian is bitter and cold, over-serving for a long time may easily hurt the yang qi of the spleen and stomach, and is contraindicated for people with deficiency of spleen and stomach (spleen and stomach weakness and cold), and used with caution for people with deficiency of yin and fluid. The drug should be used under the guidance of a doctor, do not blindly self-medicate.