High platelet aggregation rate requires pharmacologic or surgical treatment based on improvement of bad habits. Increased platelet aggregation rate reflects the increased aggregation function of platelets, which is usually seen in pre-thrombotic state and thrombotic diseases, such as myocardial infarction, angina pectoris, venous thrombosis, pulmonary embolism, hyperlipidemia and so on. In this case, first of all, we should improve the bad habits, avoid lying and sitting for a long time, and take appropriate sports to promote blood circulation when the body allows. At the same time, we should pay attention to quit smoking and drinking, and keep our diet low in fat and salt. In addition, for the blood clots have been formed or can be used under the guidance of the doctor anti-platelet drugs, such as aspirin. If it is surgery or pregnancy thrombosis patients, can give low molecular heparin sodium, warfarin and other drugs anticoagulant therapy. Preventive treatment with drugs such as aspirin is also considered for those at high risk of thrombotic tendencies, such as comorbid diabetes and hyperlipidemia. If the patient already has thrombus, the above treatment effect is not good or even the situation of thromboembolism, then timely surgical treatment should be carried out. In summary, it is recommended to consult a doctor in a timely manner to standardize the diagnosis and treatment, and follow the doctor’s instructions to use medication.