Through clinical symptoms, laboratory tests, you can determine the circumcision and syphilis. 1.Clinical symptoms: (1) Foreskin glansitis: usually caused by local physical irritation, bacterial infection and other manifestations such as erythema, swelling, local itching, pain, oozing, bleeding, blisters, low-grade fever, malaise and other symptoms in severe cases. (2) Syphilis: Stage I syphilis is manifested as hard chancre, which is a painless papule and ulcer; Stage II syphilis is manifested as flat warts in the genital area, or genital mucous membrane damages such as erythema, oedema and erosion in one or more places with clear boundaries, and the surface may be covered with grayish-white membranous material. 2. Laboratory tests: blood test for syphilis antibody is negative for glans circumcision; blood test for syphilis antibody and syphilis serology test show positive results. When discomfort occurs, it is recommended to consult a doctor in time to find out the cause and treat it as soon as possible.