Astragalus, Gui Zhi, Wu Wu Wu Tang is effective in benefiting Qi, warming the meridians, harmonizing blood and promoting paralysis, and according to the theory of traditional Chinese medicine, this formula is effective in treating cold knees caused by Qi deficiency and blood stagnation. Astragalus and Gui Zhi Wu Wu Tang is composed of Astragalus, Gui Zhi, Paeoniae Alba, Ginger and Jujubes, which is effective in benefiting Qi and warming the meridians, harmonizing Blood and promoting paralysis, and can be used in the treatment of blood paralysis, numbness and insensitivity of the skin, pain in the limbs and knuckles, sweating without wind, and a slightly astringent and tight pulse. The formula should be used with caution to avoid spicy and stimulating food during the period of taking the medicine. In addition, cold knees can also be caused by kidney yang deficiency and qi and blood deficiency. Patients with cold knees are advised to visit regular hospitals for treatment under the guidance of professional physicians.