Male testicular swelling and pain may be related to epididymitis, testicular torsion, testicular sheath effusion, ureteral stone, varicocele, etc. 1. Epididymitis: may be caused by bacterial infection, common causative organisms are E. coli, Staphylococcus aureus, retrograde infection through the urethra and cause the disease, after the onset of the disease, most of the manifestations of testicular swelling, pain. 2. Testicular torsion: it can be caused by external force, such as strenuous exercise, after torsion, there will be severe pain, need to lift the torsion as soon as possible, otherwise it is prone to ischemic necrosis, the treatment method includes manipulation reset and surgical reset. 3. Testicular syringomyelia: it may be due to the increase of syringomyelia secretion function, which leads to the increase of fluid accumulation, or it may be due to other diseases in the abdominal cavity, which forms abdominal fluid accumulation and flows into the testicular syringomyelia. After the onset of the disease, there will be a sensation of testicular swelling and a positive transillumination test. 4. Ureteral stones: When ureteral stones are present, they may also cause a feeling of soreness and pain in the testicles. 5. Varicose veins: Varicose veins can lead to poor local blood flow, accompanied by testicular swelling. There are many other causes of testicular swelling and pain in men, it is recommended to go to the hospital in time to avoid delaying the condition.