Targeted therapy and chemotherapy have different efficacy for different stages of cancer. As for which method is better, it should be chosen according to the doctor’s comprehensive judgment of the patient’s physical condition. “This treatment is generally applied to patients with weak body, which is less harmful to the patient’s body and can be used at home; 2. In terms of price, the cost of targeted therapy is more expensive. Chemotherapy is a systemic treatment that kills cancer cells with cytotoxic chemicals, which can kill cancer cells on a large scale and is the main treatment for most mid- to late-stage malignant tumors. Although chemotherapy can cause more adverse reactions, the adjuvant drugs used before chemotherapy can effectively reduce such reactions, so that patients can tolerate the stimulation of chemotherapy drugs more; 2. Disadvantages: chemotherapy drugs are not targeted compared to targeted therapy, which can kill not only cancer cells, but also normal cells. There will also be certain adverse reactions, such as nausea, vomiting, hair loss, etc., so treatment needs to be carried out through intravenous infusion under the observation of professional medical personnel. Therefore, we cannot simply say which one is better, targeted therapy or chemotherapy. We can choose one way of treatment according to the situation, or we can apply it in combination to achieve better treatment effect, which can be chosen under the guidance of doctors.