As an important umbrella for the human brain tissue, it is understandable how harmful it is once a skull defect occurs. Some people have skull defects in their lives for one reason or another, and not only is their image damaged, but their health and safety is also seriously threatened. Cranial defects have to be repaired with cranial bone repair surgery to help mitigate the damage. With a skull defect, the brain tissue is not protected by the skull, which causes the atmospheric pressure outside the skull to act directly on the brain tissue, severely damaging the brain function of the patient. The temperature outside the skull also affects the brain tissue, and uneven heat and cold are not conducive to the recovery of brain nerve function. Patients are worried, but in order to get a better recovery, patients should not have too much psychological burden, cranial defects are indeed very harmful, but as long as they receive an effective cranial repair surgery at the right time, the brain nerve function will be significantly improved after the repair. Patients with open comminuted skull fractures with good wound cleaning and no cranial hypertension are generally recommended to undergo cranial repair surgery at the first stage, while those with severe closed cranial trauma and cranial defects caused by cranial hypertension decompression, need to undergo cranial repair surgery at about 2-3 months. Currently, peek material is widely used in medicine, which is a new type of material, more advanced than bone cement, titanium mesh and other materials, and achieves a better postoperative recovery effect. peek material has high histocompatibility, strong elasticity, strong stability, and no postoperative rejection, which is the current more ideal cranial repair material.