Syphilis two injections of long-acting penicillin on the body and red spots normal. Syphilis is a sexually transmitted disease caused by infection with the syphilis spirochete. Early syphilis without treatment or incomplete treatment can develop into advanced syphilis, posing a certain risk to life. Red dots on syphilis are mainly manifested as changes in the skin and body surface of stage II syphilis. The first stage of syphilis untreated or treatment is not standardized regulation can develop into the second stage of syphilis, the second stage of syphilis widely into the body blood distribution to the whole body of the various tissues and organs, including the skin and mucous membranes, and so on. The invasion of skin tissues leads to a widespread rosacea of the skin all over the body, usually symmetrically distributed, painless and itchy rash. After 2 injections of penicillin for syphilis treatment, there are still red spots on the body which belongs to the normal situation, and it takes a certain time for the rash to subside, and it is not that the syphilis spirochete in the body is controlled and the rash disappears immediately, so it is necessary to continue the treatment, and to do the serological test regularly. Syphilis 2 shots of long-acting penicillin on the body and red spots may not be caused by syphilis, allergies or mosquito bites can also cause skin red spots, it is recommended to consult a doctor to clarify the diagnosis, so as not to delay the condition.