Generally, it takes about a month for duodenal bulbitis to start healing. However, the time may vary slightly depending on the constitution and condition of different patients, etc. Duodenal bulbitis refers to ulcers in the duodenal bulb caused by the combined action of Helicobacter pylori, gastric acid, bile, etc. on the mucous membrane of the duodenal bulb, and it can also be caused by other infectious factors, such as parasites and Mycobacterium tuberculosis. Clinical symptoms include epigastric discomfort, fullness, belching, acid reflux, nausea, vomiting, black stools and vomiting blood. The treatment of duodenal bulbourethritis mainly includes quadruple therapy, i.e., 2 antibiotics such as amoxicillin and clarithromycin + bismuth + proton pump inhibitors such as pantoprazole in combination with the treatment of Helicobacter pylori eradication, acid inhibitors such as omeprazole, and gastric mucosal protectants such as aluminum thioglycollate, and so on. In daily life, attention should be paid to the supplementation of vitamins and dietary fiber, such as fresh fruits and vegetables, etc. It is advisable to eat a light diet, avoiding the intake of cold and hard, spicy and stimulating, high oil and high salt foods such as fried chicken, hot pot, ice cream and so on. Patients should consult the doctor in time to get a clear diagnosis and follow the doctor’s instructions for treatment.