The treatment of chronic renal insufficiency includes early prevention and treatment, nutritional treatment, complication treatment and renal replacement therapy. 1. Early prevention and treatment: Early diagnosis, active and effective treatment of primary diseases, avoiding and correcting risk factors that cause the progression and deterioration of renal function are the basis of prevention and treatment of chronic renal failure, and also the key to protect renal function and delay the progression of chronic kidney disease. 2. Nutritional therapy: low-salt, low-fat, high-quality low-protein diet, protein-restricted diet is an important part of the treatment, which can reduce the generation of nitrogen-containing metabolites and alleviate the symptoms and related complications. High-quality protein includes eggs, milk, lean meat and so on. 3. Treatment of complications: correct acidosis and water and electrolyte disorders, commonly used drugs include sodium bicarbonate, furosemide, etc.; anemia treatment includes recombinant human erythropoietin, etc.; hypocalcemia, hyperphosphatemia, and renal bone dystrophy treatment includes osteoclastol, cinacalcet, etc. 4. Renal replacement therapy: including peritoneal dialysis, hemodialysis and kidney transplantation. Patients with chronic renal insufficiency should go to the hospital in time and be treated actively under the guidance of specialized physicians.