Swelling around the ankle is usually caused by ankle sprains, gouty arthritis, varicose veins in the lower extremities, hypoproteinemia and other factors. 1. Ankle sprain: Ankle sprain can cause swelling and pain around the ankle, and will be accompanied by limited foot movement. 2. Gouty arthritis: the first onset of the first metatarsophalangeal joints, followed by the dorsum of the foot, ankles, knees, etc. After the onset of the disease, the affected area may appear red, swelling, heat, pain and other symptoms, which can be relieved on their own, and the affected area of the skin can be a dark red color, with wrinkles, flaking and other phenomena. 3. Varicose veins of the lower limbs: patients can be due to superficial venous valve dysfunction in the lower limbs, so that venous blood stasis in the lower limbs, resulting in an increase in tissue fluid, swelling around the ankles, and the affected limbs can be seen to be raised veins, earthworm-like. 4. Hypoproteinemia: when plasma albumin decreases, the effective osmotic pressure will be reduced, which will cause excessive water retention in the tissues, resulting in swelling around the ankles and accompanied by lethargy, fatigue, weakness, ascites and other symptoms. In addition, nephritis, cirrhosis, pericarditis, etc. can also cause swelling around the ankles, and it is recommended to go to the hospital in a timely manner to identify the cause of the disease and receive treatment as soon as possible.