Neurological pathological signs mainly include meningeal irritation signs and pyramidal fasciculus signs. Meningeal irritation signs mainly include Kirschner’s sign, Brønsted’s sign, and cervical tonicity. Pyramidal signs include Babinski’s sign, Shattuck’s sign, Gordon’s sign, etc. If a patient has meningeal irritation signs, they are mainly seen in meningitis and may also be seen in some patients with encephalitis. Meningitis is a viral infection in which patients may have headache, nausea, vomiting, as well as physical signs and symptoms, and some patients may also have signs of meningeal irritation. Meningitis is caused by a bacterial infection. Patients mainly present with nausea, vomiting, headache and signs of meningeal irritation, which can also be seen in subarachnoid hemorrhage. Patients with subarachnoid hemorrhage mainly present with headache, nausea, vomiting, and may also present with signs of meningeal irritation. Cone bundle signs are mainly seen in cerebrovascular diseases, including cerebral hemorrhage and cerebral infarction, and also in cranial tumors. It may also occur in the case of lesions of the spinal cord, such as myelitis.