The main effect of thyroidectomy on patients is the possibility of hypothyroidism, which is manifested by mucous edema, fear of cold, weight gain and local discomfort. 1. Mucous edema: When hypothyroidism occurs, a kind of hyaluronidase activity in the body will be inhibited, and this kind of mucus-like substance containing hyaluronidase is also called mucopolysaccharides, which is usually accumulated in the skin and subcutaneous tissues, resulting in excessive water and sodium retention in the subcutaneous tissues, which will make the skin show mucous edema. 2. Fear of cold: hypothyroidism is characterized by slowing down the blood circulation of the skin at the extremities, and patients are more prone to cold than usual, mainly caused by low levels of thyroid hormones. 3. Weight gain: hypothyroidism will make people’s basal metabolic rate drop, weight gain, but weight gain is not mainly fat, but edema, due to the secretion of the thyroid hormone is not enough, the body’s metabolism will be significantly slowed down, the decomposition and utilization of subcutaneous fat slows down, and prone to water and sodium retention, which makes the patient appear obese. 4. Local discomfort: after thyroidectomy, patients will have local scar tissue in the neck, which is manifested as local discomfort. Surgery is one of the effective methods of thyroid disease treatment, thyroidectomy has some effects on the patient’s body, it is recommended to standardize the treatment under the guidance of the doctor.