In general, a full, unevenly dense uterus indicates that the patient’s uterus is large and not completely smooth, and should be further diagnosed in conjunction with the patient’s history and symptoms. Fullness of the uterus and uneven density is a description of the shape of the uterus on ultrasound, where fullness of the uterus indicates a larger than normal uterus, and uneven density indicates unevenness of the wall of the uterus. If accompanied by abdominal pain, leukorrhea and other symptoms, the patient may suffer from endometritis, adenomyosis and other diseases. 1. Endometritis: Endometritis caused by pathogen infection may result in ultrasound findings of uterine fullness and uneven density. In this case, patients should follow the doctor’s instructions to use antibiotics for treatment, and if necessary, can use surgical methods to drain pus, clean the uterine cavity. 2. Adenomyosis: Adenomyosis generally refers to the invasion of the glands and mesenchyme of the endometrium into the muscular layer of the uterus, causing atrophy and necrosis of the endometrium. This disease also leads to an increase in the size of the uterine cavity and an uneven density of the uterine muscular layer. It is recommended to treat the disease with medication as prescribed by the doctor, and surgery can be performed if necessary. If the ultrasound findings are fullness and uneven density of the uterus, the cause of the disease should be clarified based on the history and symptoms under the supervision of a doctor and treatment should be actively pursued.