Male breast enlargement for more than ten years can be treated mainly by medication and surgery. 1. Drug treatment: The occurrence of this disease is related to the high estrogen level or elevated estrogen/androgen ratio in men. Clinically, commonly used medications for breast enlargement can be used to improve the symptoms, and commonly used medications include Easy Pill, Xiaojin Pill, and Hongjin Xiejie Capsules. 2. Surgery: If breast hyperplasia leads to gynecomastia, surgical treatment can be considered. The common surgical method is subcutaneous adenomectomy, which can be done by lumpectomy or general open surgery, and the surgery usually involves the removal of all the breast tissues through the circumareolar approach. If the patient has breast hyperplasia, it is recommended to go to the regular hospital for examination, cooperate with the doctor’s treatment, the drug should be applied under the guidance of the doctor.