Myositis Antibody Profile 16 is an important and specific test for detecting inflammatory myopathies, including several antibodies including MDA-5, Jo-1, Ro-52 and others. Inflammatory myopathy is an autoimmune disease that includes several types such as polymyositis, dermatomyositis, and dermatomyositis without myopathy. The specific pathogenesis is still not very clear, the disease is more dangerous, especially MDA-5-positive patients with this type of anaplastic dermatomyositis, tends to progress more rapidly, and many will develop severe interstitial pulmonary fibrosis, need to be treated with high-dose glucocorticoids and gammaglobulin, but many patients with a poor prognosis and a high mortality rate.