Smoking can have adverse effects on sexual function and reproduction. The smoke produced by smoking contains a variety of harmful substances, such as nicotine, formaldehyde, N-nitrosamines, etc., which can affect human reproduction, sexual function and developmental function. Such as damage to genetic material, fallopian tube function, fertilization function, placental function, fetal cardiovascular system, fetal development and other aspects. Currently, there is ample evidence that women who smoke have a reduced likelihood of conception and experience fetal growth restriction, placenta previa, placental abruption, low birth weight of the newborn, and sudden infant death syndrome (SIDS). In addition, there is evidence that smoking can cause erectile dysfunction, decreased sperm motility and abnormal sperm morphology in men, ectopic pregnancy and spontaneous abortion in women. In addition to the above, smoking is also associated with malignant tumors, such as lung, stomach, and bladder cancers. Smoking is associated with respiratory-related diseases such as chronic obstructive pulmonary disease and juvenile asthma. Smoking is associated with cardiovascular diseases such as atherosclerosis and peripheral arterial diseases. Smoking is harmful to health, tobacco control is the best strategy for disease prevention, and quitting smoking is the only proven way to reduce the harm of smoking.