Monkeypox virus is a virus of the genus Orthopoxvirus, and when infected, the patient’s skin will show symptoms such as maculopapular rash, small blisters and pustules. Monkeypox virus belongs to the genus Orthopoxvirus, and the virus is brick-type or oval-type, which can be transmitted through body fluids, blood, droplets and other means in animals and people. When humans are infected with monkeypox virus, they will show a series of symptoms on the skin. Initially, a rash will appear, and the shape of the rash will gradually change from a flat papule at the bottom to a small blister, and then from a fluid-filled blister to a pustule, which will rupture and form a crust on the affected area, and the crust will gradually fall off after about three weeks. Monkeypox virus is extremely strong, there is no effective treatment, the principle of treatment is to isolate the patient, prevention of skin lesions, secondary infections, it is recommended that the body after the appearance of symptoms related to monkeypox virus infection to consult a doctor in a timely manner.