Drugs used to treat hypertension include diuretics, beta receptor antagonists, calcium channel blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor antagonists.
Diuretics are most commonly used in the thiazide group, such as hydrochlorothiazide. The effect of antihypertensive is slow and smooth, and the effect is relatively long-lasting. They are effective in mild and moderate hypertension, but can also be used in salt-sensitive hypertension, simple systolic hypertension, with obesity, diabetes or heart failure, menopausal women and the elderly.
Beta receptor antagonists (such as propranolol, etc.) have a strong and rapid onset of antihypertensive effect, and the duration of action varies with different drugs. They are effective in different degrees of hypertension, especially in middle-aged and young people with fast heart rate, and chronic heart failure with angina pectoris.
Calcium channel blockers (such as nifedipine, verapamil, etc.) have a more rapid onset of antihypertensive effect, relatively strong antihypertensive efficacy and amplitude, with obvious effects on blood lipids, blood sugar, etc., and better antihypertensive efficacy in elderly patients, and significant antihypertensive effect in alcoholic patients. It is suitable for patients with coronary heart disease, diabetes mellitus and peripheral vascular disease, and long-term treatment can resist atherosclerosis.
Angiotensin-converting enzyme inhibitors have the effect of improving insulin resistance and reducing urinary protein, and have better efficacy in hypertension accompanied by heart failure, infarction, atrial fibrillation, proteinuria, reduced glucose tolerance or diabetic nephropathy.
Angiotensin receptor antagonists have a slow but smooth and long-lasting effect. They have the same target group as angiotensin-converting enzyme inhibitors.
Please follow your doctor’s instructions for specific dosing regimens.