Collagenase discolysis Collagenase, which can specifically hydrolyze the three-dimensional helix structure of natural collagen under human physiological PH and temperature conditions without damaging other proteins and tissues. Because of this chemical characteristic, collagenase for injection can be injected into the herniated disc or disc or nucleus pulposus to selectively dissolve the herniated nucleus pulposus and annulus fibrosus, thus relieving the nerve root compression at the herniated site and achieving the purpose of treating lumbar disc herniation, which is called collagenase discolysis. This method is highly targeted, easy to learn, low cost, safe, less invasive, and can achieve high efficacy by puncture injection only. It is one of the main minimally invasive treatment methods for early lumbar disc herniation and is still widely used in clinical practice. Ozone (O3) Minimally Invasive Technology Introduction In recent years, ozone (O3) has been used in Europe and other advanced countries to treat herniated cervical and lumbar discs, which is characterized by its simplicity and safety, low injury, good efficacy and quick recovery of patients. In addition, O3 can also be used for the treatment of arthritis, frozen shoulder disease, trauma and refractory ulcers, anti-free radical anti-aging, stroke and viral hepatitis. In recent years, many hospitals in China have introduced this technology, and our hospital started this technology earlier in 2006, and has treated nearly 1,000 patients including those in the peninsula and surrounding areas, with a 100% puncture success rate and over 90% efficiency, which is very popular among patients. The mechanism of action includes: 1, oxidation: O3 has unstable characteristics and strong oxidation ability. 60μg/ml of O3 concentration can fully oxidize and decompose proteins and polysaccharide macromolecules in the nucleus pulposus, and the volume of the nucleus pulposus is gradually reduced by oxidation, and the compression of the nerve root disappears; 2, anti-inflammatory effect: by antagonizing the release of immune factors in the inflammatory response, dilating blood vessels, improving venous reflux, reducing nerve root edema and mucosity, and reducing nerve root edema. The strong oxidizing effect of O3 can rapidly inactivate the above inflammatory chemicals and achieve pain relief. The strong oxidation of O3 can quickly inactivate the above inflammatory chemicals and achieve analgesic effect. Introduction of Radiofrequency Minimally Invasive Technology The mechanism of radiofrequency thermocoagulation is to emit high frequency radiofrequency current through a magnetic field, which generates a changing magnetic field at the tip of the working electrode, causing molecular movement and frictional heat generation in the target tissue covered by the magnetic field, and thermally coagulating and destroying the target tissue. Radiofrequency thermal coagulation target treatment is accurately positioned under C-type X-ray machine and monitored under digital subtraction, which directly denatures and coagulates the nucleus pulposus of the protruding disc; shrinks and reduces the volume and relieves the compression. It does not hurt the normal nucleus pulposus tissue, and at the same time repairs the rupture of the fibrous ring, inactivates the nerve endings of the nascent lesions in the disc, directly blocks the release of glycoprotein and beta protein in the medullary fluid, and the warming effect plays a good therapeutic role on the injured fibrous ring, edematous nerve roots and inflammatory reactions in the spinal canal, and the symptoms disappear or are reduced immediately after treatment. It is one of the minimally invasive treatment methods that are internationally recognized as being safe and effective, with little patient pain and low risk. Lumbar laser disc therapy (PLDD) Percutaneous perforated laser disc decompression is a procedure in which a 16G/18G puncture needle is used to puncture the diseased cervical/lumbar disc under the guidance of C-arm X-ray or CT, and a 200-800 m diameter optical fiber is guided through the puncture needle. PLDD is indicated for contained disc herniation with intact annulus fibrosus and radicular symptoms consistent with the disc lesion segment. PLDD. Minimally invasive electric disc rotational cutter (abbreviated: rotational cutter) uses battery as the energy source and micro motor as the power source to remove the disc nucleus pulposus lesion tissue using the world’s advanced minimally invasive disc surgery technology, so as to reduce the pressure of the disc and relieve the pain of the patient. The rotary cutter was originally developed successfully by Stryker in the United States and introduced into China in 2005, achieving good clinical results. Treatment mechanism: Using minimally invasive surgical techniques, using a battery as the energy source and a micro motor as the power source, a special rotary cutter bit is used to perform percutaneous disc puncture and decompression through a puncture needle on patients with intervertebral disc lesions using an X-ray machine. The rotary cutter has the following features in the treatment of discogenic low back pain: 1. Minimally invasive and effective. The effectiveness rate reaches 90~95%. 2, can reduce the pressure of the disc or remove the herniated nucleus pulposus. 3, electric high-speed rotary cutting. 4.Less pain. 5.Little damage. 6.Fast recovery. 7.No obvious scars after surgery. Indications: 1.Lower back pain with lower limb radiating pain or lower limb pain caused by lumbar disc herniation. 2.There is objective evidence that lumbar disc herniation is the cause of low back pain, including positive straight leg raising test and positive strengthening test; confirmed by imaging examination (including X-ray, MRI, CT, discography). 3, Belongs to contained disc herniation (intact fibrous annulus). 4.Disc height cannot be <70% of normal disc height. 5, by other conservative treatment (such as drug therapy, physical therapy or epidural cavity injection and other therapies), the effect is not good.