Medical microwave is a high frequency electromagnetic wave with a frequency of 300-300,000 MHZ and a wavelength of 1mm-1m, which is used to inactivate tumor tissues directly by its special heat generation effect. Most of the human tissue is composed of polar molecules such as water and protein, under the action of microwave electric field moment, polar molecules along the direction of the microwave electric field for the orderly arrangement of the orientation of the movement, and with the alternating high-frequency electric field and back and forth rotation, in the process of rotation and adjacent molecules produce similar friction, collision and generate heat, microwave is a kind of internal heating method, and heat does not emit, balanced, good thermal stability. The microwave is a kind of internal heating method, and the heat is not radiated, balanced and heat stable. The brief process of surgical operation includes: under the premise of “inter-compartmental” concept, the important nerves, blood vessels and other tissues around the lesion are separated and protected, and the tumor and tumor segment bone are exposed according to the principle of enlarged resection of malignant tumor, and the tumor tissue is inactivated by temperature control through the inserted microwave antenna, and the surrounding healthy tissues are protected by cooling. The tumor and tumor segment bone are exposed according to the principle of extended malignant tumor resection. The inactivation time is determined according to the “temperature-time” curve, and the bone defect formed after the tumor inactivation is reconstructed with allograft bone and bone cement, and internal fixation is performed if necessary. The advantages include: (1) Only the in situ separation of the tumor (including the important blood vessels and nerve bundles and uninvaded muscles) is performed, which preserves the stability and continuity of the bone and joint structures and maximizes the function of the limbs and joints; (2) The microwave is introduced into the center of the tumor by a special wire, so that the high temperature generated is transmitted from the inside to the surface. (2) The microwave is introduced into the center of the tumor by a special wire, so that the high temperature generated is transmitted from the inside to the surface, which can kill the tumor cells without destroying the continuity of the bone and minimizing the damage to normal tissues, and the microwave antenna is placed in a way that reduces the radiation damage to the patient’s body and medical personnel. (3) The surface temperature of the tumor can be above 50℃ and the central temperature can be 108℃, thus ensuring that all the tumor cells can be killed, while using the high temperature heat conduction effect of microwave and sufficient action time, the tumor area can be thermally inactivated in an extended range to ensure a sufficient surgical safety boundary and reduce the possibility of local recurrence after surgery; (4) After the removal of the lesion, the autologous bone shell is preserved, which facilitates reconstruction and is expected to obtain complete bone healing through bone grafting; (5) In addition to the thermal effect, microwave also induces an anti-tumor effect. (5) In addition to the thermal effect, microwave also induces an anti-tumor effect, which may be due to T-cell or N K-cell-mediated immune response.