How long can remove the drain after ERCP is decided according to the condition, generally 3~5 days can be removed, patients with more stones extended to 7~10 days, bile duct stenosis depends on the situation. 1. 3~5 days: For patients with bile duct stones, after ERCP stone extraction, the drain is usually placed for 3~5 days, and an imaging is needed before removal, and the drain can be removed if there are no stones left. 2. 7~10 days: For some patients with recurrent conditions and more biliary stones, the drainage time needs to be extended, and the drain needs to be placed for about 7~10 days, waiting for the bile duct to drain smoothly before removal. 3. Depending on the situation: if the obstruction caused by tumor or bile duct stenosis patients, the drainage tube plays the role of stent, the time of removal should be based on the specific conditions, if the retention of drainage tube during the emergence of acute pancreatitis, biliary bleeding and other complications, also need to wait until the condition is under control before pulling out. After ERCP, we should pay attention to the observation of the drainage fluid, to ensure that the patient’s condition is recovered before removing the drainage tube, if there is any discomfort, please consult the doctor in time, so as to avoid delaying the condition.