Hypothyroidism or post-thyroid surgery due to thyroid gland removal, thyroid function will be affected, the need to apply levothyroxine replacement therapy, there are many patients and friends worried, in fact, oral thyroxine is not terrible. 1, safe: pregnant women can eat. 2, convenient: once a day, half an hour before breakfast orally or before bedtime. 3, the price is not expensive: about 1 yuan per day. Note: Since levothyroxine will accelerate the loss of calcium, it is recommended to take levothyroxine orally with appropriate calcium supplementation, preferably with a calcium and vitamin D complex. Especially postmenopausal women should pay more attention to calcium supplementation. Calcium supplementation should be around 1000 mg per day and vitamin D3 (e.g. Calcium D600, 1 capsule/time, 2 times/day) to prevent osteoporosis after differentiated thyroid cancer surgery. Sodium levothyroxine (Eugenol, Retis or domestic levothyroxine tablets) is currently available in 25 mcg, 50 mcg and 100 mcg dosage forms. When taking the medication, you must pay attention to the dosage, not by the tablet, but according to the dose!