Women are not interested in sex mainly for the following reasons: 1, the most common is the emergence of endocrine disorders, such as sex hormone abnormalities, common androgen secretion, androgen secretion abnormal increase in estrogen secretion, or the emergence of abnormal thyroid function, such as hypothyroidism. If the above diseases appear, it is easy to cause sexual indifference; 2, may be the emergence of psychological diseases, such as depression, anxiety, once these diseases, patients may be depressed mood, pain, reluctance to appear sex life or for sex life is particularly nervous, anxiety, fear, it will be easy to sex life is not interested, serious time to have a rejection and aversion to sex life; 3, may be 3, may be the cause of menopause syndrome, such as women to the menopause is easy to appear abnormal libido, mainly because of the rapid changes in sex hormone secretion and stress, while many physical symptoms, so mood irritability, anxiety, it is easy to appear on sex life is not interested in the problem; 4, may also be social, life and stress factors, such as stress, economic burden is too much, the husband and wife relationship is not good These social factors can easily lead to a great reduction in desire, especially a reduction in libido, which can easily lead to disinterest in sexual life at this time. The above reasons are more common and must be actively treated and handled.