Patients with gout may experience pain in one or more joints throughout the body, commonly in the first metatarsophalangeal joint, and the location of the pain may vary due to individual variability. Gout is a disease caused by high blood uric acid levels that lead to the deposition of urates in the joints, and patients may experience a range of symptoms. It can be caused by genetic factors, medications, intake of purine-rich foods, alcohol consumption and other factors. Gout may affect one or more joints throughout the body, such as the hands, feet, knees, heels, elbows and other parts of the body, and is commonly seen in the unilateral first metatarsophalangeal joint. Symptoms of severe pain in the affected joints, mostly occurring suddenly at midnight or early in the morning, may also appear red, swollen, hot, dysfunction and other symptoms, some patients deposited a large number of gout stones in the joints, which can lead to the destruction of joint bone, resulting in joint deformity, and ultimately disability. Once the patient has symptoms suspected of gout, it is recommended to go to the hospital in time to clarify the cause of the disease and take relevant treatment measures under the guidance of the doctor.