Viagra, known generically as sildenafil, is not usually recommended to be taken together with irbesartan hydrochlorothiazide tablets. Sildenafil belongs to the cyclic guanosine monophosphate specific type 5 phosphodiesterase selective inhibitor, after use can relax the cavernous smooth muscle of the penis, so that the blood flow into the cavernous body of the penis, so that in the role of sexual stimulation, so that the penis can be erected to complete sexual intercourse, is mainly used for the treatment of erectile dysfunction. However, low blood pressure, palpitations, heart failure and other discomforts may occur after taking it. Irbesartan hydrochlorothiazide tablets belong to the compound preparation, after use can reduce extracellular volume, reduce peripheral vascular resistance, as well as can inhibit vasoconstriction and the release of aldosterone, so as to play the role of lowering blood pressure, mainly used in the treatment of hypertension. In summary, coadministration of Irbesartan Hydrochlorothiazide Tablets and Sildenafil may lead to symptoms of low blood pressure, so coadministration is not recommended. If necessary, the specific dosage and precautions should be decided after the doctor’s comprehensive assessment of the condition.