Neostigmine Efficacy and Effects

Neostigmine is an anticholinesterase drug, mainly used in the treatment of myasthenia gravis and intestinal paralysis after abdominal surgery. Neostigmine inhibits cholinesterase and exerts a complete cholinomimetic effect, which excites skeletal muscle. At the same time, it also has the effect of excitation of gastrointestinal smooth muscle and excitation of glands, eyes, cardiovascular and bronchial tubes. Neostigmine is mainly used in the treatment of myasthenia gravis and intestinal paralysis after abdominal surgery. It is also used in the treatment of paroxysmal supraventricular tachycardia and others. Adverse reactions mainly include profuse sweating, nausea, vomiting and diarrhea. It is contraindicated in patients with mechanical intestinal obstruction and urinary tract obstruction. The use of specific drugs should be carried out under the guidance of a doctor, and should not be used arbitrarily.