Hyperthyroidism cannot be diagnosed by touching the neck. Diagnosis of hyperthyroidism requires a complete physical examination, laboratory tests (thyroid function tests) and imaging tests. 1. Physical examination: patients usually have varying degrees of goiter; nodular goiter with hyperthyroidism can be palpated as nodular enlargement of the thyroid gland. Eye examination: protruding eyes are a characteristic manifestation of hyperthyroidism. Cardiovascular examination shows an increased heart rate and a hyperactive apical first heart sound. Other tests such as skin is often warm, moist and sweaty. 2. Laboratory tests (e.g. thyroid function tests): thyroid stimulating hormone (TSH): the most sensitive indicator of thyroid function. Serum total thyroxine: the main indicator for diagnosing hyperthyroidism. Serum free thyroid hormone: closely related to the biological effect of thyroid hormone, is the main indicator of diagnosis of clinical hyperthyroidism.TSH receptor antibody: an important indicator of diagnosis of Graves’ disease. 3. Imaging examination: patients with hyperthyroidism Graves’ disease have rich blood flow in the thyroid gland, and the diameter of thyroid nodules in patients with autonomous high-functioning adenomas is usually more than 2.5cm, which can be examined by thyroid ultrasound or magnetic resonance imaging. Ocular CT and MRI can help to rule out proptosis due to other etiologies. Thyroid radionuclide scan is mainly used for differential diagnosis of hyperthyroidism. If there is any abnormality in the relevant examination, go to the hospital as soon as possible for consultation and individualized diagnosis and treatment plan according to the specific condition.