Laparoscopic Radical Gastric Cancer Surgery

  Gastric cancer (gastric canrcinoma1) is the most common gastrointestinal malignant tumor in China, with about 400,000 new cases of gastric cancer in China every year, and the mortality rate accounts for 23.02% of all malignant tumors, ranking the first among all kinds of cancer deaths. Gastric cancer is more common in men above 50 years old. There are many predisposing factors for gastric cancer, such as geographical environment and dietary factors (e.g. coastal areas, long-term consumption of salt cured food, smoking1, H. pylori infection, precancerous lesions (e.g. gastric polyps, adenomas, heavy anisotropic hyperplasia of mucosal epithelium1, genetic and genetic changes, etc.). According to the site of tumor occurrence, it can be divided into sinus cancer, fundic cancer, gastric body cancer, etc. According to the degree of tumor invasion, it can be divided into early, intermediate and advanced gastric cancer, and the latter two are collectively called progressive gastric cancer. Gastric cancer can directly infiltrate the stomach wall and abdominal tissues, spread and metastasize to other parts of the body along the blood system (such as liver, lung, bone metastasis1, peritoneal spread metastasis, lymphatic metastasis, etc.).  Early gastric cancer often has no specific symptoms, but with the progress of tumor, more obvious symptoms may appear, such as pain, emaciation, nausea, vomiting, vomiting blood, anemia, black stool, abdominal mass, and advanced patients may develop malnutrition and cachexia. Gastric cancer can be detected through barium X-ray, fiberoptic gastroscopy with tissue biopsy, abdominal ultrasound, spiral CT, tumor marker test (such as CEA, ca1991, etc.).  The diagnosis and treatment of gastric cancer emphasize early diagnosis and comprehensive treatment mainly by surgery. Surgical resection is the main means of gastric cancer and the only possible cure for gastric cancer at present. Since most gastric cancer patients in China are middle to late stage patients when they are found, the 5-year survival rate after radical surgery for gastric cancer is about 30%.  Surgical treatment is divided into two categories: radical surgery and palliative surgery. The principle of radical surgery requires removal of part or all of the stomach, including the cancerous lesion and the potentially infiltrated stomach wall, and removal of the lymph nodes around the stomach according to the clinical staging criteria, as well as reconstruction of the digestive tract. Radical surgery depends on the tumor site, progression and clinical stage, for example, early gastric cancer can be treated by open or laparoscopic partial gastrectomy. When the primary lesion cannot be resected, palliative gastrectomy or various short-circuit procedures such as gastrojejunostomy are performed to relieve complications such as obstruction and perforation.  The world’s first gastrectomy for gastric cancer was performed by Dr. Billoth in 1881, and the surgical treatment of gastric cancer has been developed for more than 120 years. The traditional open surgical approach requires a 10-15 cm long incision in the abdominal wall, where the surgeon performs various operations under direct vision and can expose the surgical field well. Traditional open surgery is still the main means of surgical treatment because of its mature technology and accumulated experience, but open surgery has disadvantages such as large surgical trauma, postoperative incision pain, infection and long hospital stay because of the scope of operation and abdominal incision is often large. With the progress of modern treatment concept and medical instrument technology, laparoscopic technology has been developed in the field of gastrointestinal tumor treatment. In 1994, Dr. Kitano in Japan used laparoscopy for the first time to treat early gastric cancer and achieved satisfactory results, and since then, minimally invasive gastric cancer treatment represented by laparoscopic radical gastric cancer treatment has been widely carried out in the world. Since then, minimally invasive gastric cancer treatment represented by laparoscopic radical gastric cancer treatment has been widely carried out worldwide, and more experience has been accumulated in China.  Laparoscopic radical gastric cancer treatment also follows the principles of traditional open surgery for radical tumor treatment, i.e.: 1) emphasis on whole block resection of tumor and surrounding tissues; 2) non-contact principle of tumor operation; 3) adequate margins; 4) thorough lymph node dissection. Laparoscopic radical gastric cancer surgery has the following advantages over traditional surgery: 1. less trauma, faster postoperative recovery and aesthetic appearance; 2. less impact on patient’s immune function; 3. good coagulation effect of ultrasonic knife can reduce the shedding of tumor cells from lymphatic vessels during lymph node clearance, which is a safe and feasible surgical method for radical treatment of early gastric cancer and part of progressive gastric cancer. Meanwhile, it has the advantages of minimally invasive surgery such as light postoperative pain, fast recovery of intestinal function and short hospitalization time. Developed countries such as Japan have recommended laparoscopic radical gastric cancer surgery as one of the standard treatment options for early stage patients.  According to the classification of laparoscopic techniques, laparoscopic radical gastric cancer treatment is the standard treatment for early stage patients. Laparoscopic radical surgery for gastric cancer is divided into three types of procedures: complete laparoscopic radical surgery for gastric cancer, hand-assisted laparoscopic radical surgery for gastric cancer and laparoscopic-assisted radical surgery for gastric cancer.  1.Completely laparoscopic radical gastric cancer surgery: all operations can be performed under laparoscopy, which requires high skills and instruments of the operator and causes the least trauma to the patient.  2.Hand-assisted laparoscopic radical gastric cancer surgery: It is combined with traditional open surgery, in which a small incision is made in the abdominal wall and through a special device, the surgeon can reach into the abdominal cavity with his hand, and the operator can use his hand to explore the internal organs, stop bleeding and perform lymph node dissection, etc., which reduces the difficulty of surgery.  3.Laparoscopic assisted radical gastric cancer surgery: Most of the surgical operations are completed under the surveillance of laparoscope, and finally the gastrointestinal tube is dragged out of the abdominal cavity for resection and anastomosis through a small auxiliary incision in the abdominal wall. Nowadays, laparoscopic-assisted gastric cancer surgery is most commonly used, reflecting the superiority of minimally invasive and the effectiveness of radical gastric cancer surgery.  Compared with traditional open surgery, the main clinical advantages of laparoscopic radical gastric cancer surgery are as follows: 1. Laparoscopic radical gastric cancer surgery is characterized by good recent postoperative results, small incision, fast postoperative recovery and shortened hospital stay, and has little impact on patients’ immune function, which is conducive to improving patients’ postoperative quality of life. 2. Many studies in recent years have shown that laparoscopy can technically achieve the same adequate margin cutting and lymph node dissection as open surgery. and lymph node dissection, which are safe and effective for the treatment of early and progressive gastric cancer and achieve the effect of radical treatment. With the further development and maturation of laparoscopic radical gastric cancer treatment, laparoscopic radical gastric cancer treatment will definitely be used more often in the surgical treatment of gastric cancer.