Smoke syndrome, also known as smog disease, is primarily a cerebrovascular disease. The reason why it is called smoky disease is because when a cerebral angiogram is given, it resembles like smoke on the image, so it is called smoky disease. Discovered by Japanese medical doctors, smog disease is a condition in which a person’s cerebral blood vessels gradually become narrowed or even occluded, often with a sudden onset of cerebrovascular disease, either ischemic or hemorrhagic. Current research on smog disease suggests a genetic predisposition, as well as a link to infectious and immunologic factors. For the treatment of smoky disease, internal medicine conservative treatment can be given to patients with ischemic symptoms to expand blood vessels and improve vascular treatment; if the symptoms are hemorrhagic, it can be given to patients with hemostasis and lowering of cranial pressure treatment. At the same time, we can also consider giving hormone therapy, and if necessary, we can consult neurosurgery to give surgical treatment. The current surgical program can carry out direct bypass, or indirect bypass, and so on.