Itchy skin in uremia is mainly caused by toxin stimulation, hyperphosphatemia and dry skin. 1. Toxin stimulation: uremia patients due to the presence of urinary disorders, the body’s toxins can not be discharged in a timely manner, including urea, creatinine, etc., toxins in the body a large number of accumulation, may cause irritation of the skin, thus causing itching skin. 2. Hyperphosphatemia: patients with uremia often have hyperphosphatemia, a relatively common electrolyte disorder, often leading to itchy skin, and most of them are generalized itchy skin. 3. Dry skin: uremia patients are not able to drink water normally, so they tend to have dry skin, and are prone to itchy skin. Uremia itchy skin, and may be caused by other reasons, should be timely to the regular hospital to take comprehensive treatment to control the condition.