Abnormal fecal passage is a common disease in life and has always been accompanied by human progress and medical development. It is not only an independent condition but also a symptom of a disease. In addition, abnormal stool process often affects life and work. Since abnormal fecal excretion process is caused by a variety of etiologies, the symptoms of abnormal fecal excretion process are present in all clinical diagnoses, but their nature is different. Therefore, the differential diagnosis of fecal abnormalities caused by different causes should be made. Differential diagnosis of abnormal fecal excretion process: 1, chronic bacterial infection, multiple fecal routine and culture positive findings, as well as adequate and effective antibiotic systemic treatment, symptoms improve significantly, can be clearly diagnosed. 2, chronic amoebic dysentery Multiple stools looking for amoeba and metronidazole test treatment can be clearly diagnosed. 3.Gastrointestinal endocrine tumor Gastrinophilic tumor can appear severe diarrhea and intractable ulcer disease, serum gastrinophilic level is very high, general treatment is ineffective. Vasoactive intestinal peptide tumor (Vipoma) also causes severe diarrhea; serum VIP level is increased. 4, malabsorption syndrome There is diarrhea, resulting in an abnormal fecal excretion process, but there is often fat and undigested food in the stool. 5.Intestinal tumors Small benign tumors of the small intestine can occur with diarrhea and intermittent episodes of partial intestinal obstruction. Colonic tumors can also present with symptoms similar to functional intestinal disorders. Attention should be paid especially to the elderly. Barium x-ray imaging or colonoscopy can be performed to clarify the diagnosis.