Symptoms of chest pain after smoking may be angina caused by coronary atherosclerotic heart disease. Smoking is an independent risk factor for coronary atherosclerosis. Long-term smoking may accelerate the process of coronary atherosclerosis in patients, resulting in narrowing of coronary arteries and insufficient blood supply to the heart muscle, which makes it easy for angina symptoms to occur. Patients suffering from angina pectoris often experience chest pain in the precordial region. This pain is especially aggravated during exertion or strenuous activities. And the pain will be relieved after the patient rests or takes nitroglycerin orally. In this case, it is necessary to go to the hospital to check the electrocardiogram, cardiac ultrasound, and coronary artery CT to make a clear diagnosis. Patients suffering from coronary artery disease can be treated with drugs that improve the blood supply to the coronary arteries, and in severe cases, interventional surgery or cardiac bypass surgery may be needed. Chest pain, may be suffering from viral myocarditis, pleurisy, intercostal neuralgia and other diseases. It is necessary to complete the relevant examinations to clarify the diagnosis and carry out targeted treatment according to the cause of the disease.