The blood concentration and absorption of valsartan hydrochlorothiazide is not very much related to meals and can be taken at any time, it is recommended to take it in the morning after waking up, and it needs to be taken at a fixed time of the day. Valsartan hydrochlorothiazide is a combination of valsartan and hydrochlorothiazide. Both drugs are absorbed rapidly after oral administration and are little affected by meals, so the bioavailability and efficacy of the drug are similar when taken on an empty stomach and after meals, and can be taken at any time. However, considering the physiological fluctuation of human blood pressure, it is recommended to take it after waking up in the morning, which can inhibit the rise of blood pressure around 10 am and keep the blood pressure stable throughout the day. Valsartan Hydrochlorothiazide is recommended to be taken at the same time every day as it usually needs to be taken only once a day due to the long duration of its effect. Valsartan Hydrochlorothiazide is mainly used to treat high blood pressure and other conditions. The drug is contraindicated in drug allergy, pregnant women, severe hepatic and renal failure, anuria, hypokalemia, hyponatremia, hypercalcemia, hyperuricemia. Cautious use of the drug is recommended for breastfeeding, exercise sources, and people who need delicate manipulation. The drug needs to be used under the guidance of clinicians, and if symptoms such as hypokalemia, urticaria, vomiting, postural hypotension, headache, etc. occur during the use of the drug, it is recommended to stop the drug and seek medical attention.