Granulomas that don’t go away and hard bumps usually require surgery. In longer-term wheals, granulomas have often formed within the bumps. At this time, if the granuloma continues to be treated conservatively with warm compresses and antibiotic medications such as levofloxacin eye drops, the effect is usually less than ideal, and it is difficult to make the bumps go away, so surgery is usually needed to incise the bumps. This is usually done under local anesthesia, either by incising the pimple from the skin surface or from the conjunctival surface of the eyelid, to remove secretions, including granulomas, from the pimple. It is important to make sure that the secretions, including granulomas, are completely removed from the lump when the procedure is performed. Once the contents are removed, the granuloma will gradually heal. If the granuloma does not go away, it is recommended that the patient seek medical attention.