The overall level of pain in colonoscopy patients is average. Clinical studies have shown that whether colonoscopy is painful and the severity of the pain is related to the examination method, the examiner’s familiarity, the patient’s individual situation and other factors under the same colonoscopic conditions, and cannot be generalized. At present, colonoscopy in China mainly uses a single person to operate the examination, and the patient can feel slight abdominal pain during the examination. For especially nervous or abdominal surgery intestinal adhesion patients, as well as younger children can be under anesthesia for painless colonoscopy, the patient can be more than ten minutes to complete the examination, the examination process is usually painless and less risky, but the cost of the examination will increase. In addition, the level of operation of the examining doctor has a certain impact on the patient’s pain. If the doctor’s operation level is high, he or she will minimize the number of times the colonoscope pulls on the intestinal wall and reduce the patient’s discomfort level. Patients who are frequently constipated have a long and curved colon and therefore experience more pain than patients with diarrhea. Patients with a history of abdominal and pelvic surgery who require colonoscopy should see a doctor who has some experience in operating the procedure, which can reduce discomfort to some extent. Those who have difficulty with plain endoscopy should choose to undergo painless colonoscopy.