Cold and flu generally refers to the common cold, commonly known as “cold”, is caused by viral infections, mainly symptomatic supportive treatment, commonly used drugs for the treatment of cold and flu antihistamines, antipyretic and analgesic drugs, reduce nasal mucosal congestion drugs, cough suppressants, and so on. 1. Antihistamines: mostly used for frequent sneezing, runny nose and other symptoms. Antihistamines can block histamine receptors, inhibit vasodilation and thus reduce vascular permeability. Commonly used drugs are loratadine, cetirizine and so on. 2. Antipyretic and analgesic drugs: mostly used for patients with headache, fever and other symptoms. Commonly used drugs are ibuprofen, acetaminophen and so on. 3. Reduce nasal mucosal congestion: mostly used for patients with nasal congestion, post-nasal drip symptoms, can be given pseudoephedrine treatment to reduce nasal congestion. 4. Cough suppressants: mostly used for patients with dry cough. Cough suppressants can inhibit the medullary center, so that it can achieve the effect of cough. Commonly used drugs include dextromethorphan and codeine. In addition to the above symptomatic treatment, patients with colds also need to pay attention to rest, drink plenty of water, maintain indoor air circulation and prevent secondary bacterial infections. The above medications should be used in a standardized and rational manner under the guidance of professional physicians and pharmacists.