Thickening of the lumen at the beginning of the basilar artery, the cause should be clearly identified in order to choose the best treatment. If it is caused by atherosclerosis, the main treatment is to give antiplatelet aggregation, plaque stabilization and other treatments. If there is a localized aneurysm or arterial entrapment, appropriate surgical treatment or observation with follow-up dynamic review should be chosen according to the condition. The thickening of the lumen at the beginning of the basilar artery may be related to vascular atherosclerosis, and it is usually recommended that the patient should insist on applying antiplatelet aggregation drugs, such as aspirin, and lipid-lowering and plaque-stabilizing drugs, such as atorvastatin; and controlling the risk factors, quitting smoking and drinking, and controlling the blood pressure, blood lipids, and blood glucose. Prevent disease progression by the above ways. If it is clearly diagnosed through vascular CTA examination or angiography, and there is a local aneurysm or arterial entrapment, the severity of the condition needs to be further assessed; if the risk is not great, it can be dynamically observed first, and the vascular CTA or angiography can be periodically reviewed to assess whether there is any progress; if the risk is increased, the condition can be treated by surgery. It is recommended that patients seek timely medical treatment and standardize the treatment under the guidance of doctors.