The nine-valent vaccine is not recommended for patients while taking cold medicine. Nine-valent vaccine usually refers to the nine-valent HPV vaccine, which is used to prevent cervical cancer caused by human papillomavirus (HPV) infection. Generally, the immune function of the body decreases while the patient is taking cold medicine. If the patient is vaccinated with the nine-valent HPV vaccine at this time, the body may not be able to produce sufficient and effective antibodies, thus failing to achieve the purpose of the vaccine and prevention of the disease. In addition, cold and flu patients may also be accompanied by cough, headache and other symptoms, if this time to vaccinate the nine-valent HPV vaccine, some patients may not be physically tolerated, easy to aggravate the symptoms of the cold and flu. Therefore, it is recommended to wait until the cold is cured and medication is stopped, the body’s immune function returns to normal, and the body is in good condition before receiving the vaccine. In addition, before receiving any vaccine, you should truthfully inform your healthcare provider about your health condition and recent medication to rule out any contraindications to vaccination.