Generic name of Viagra is Sildenafil, high blood pressure is usually not suitable for taking Avanafil with Sildenafil, and need to be used carefully under the guidance of a doctor. 1. Avanafil is used to treat erectile dysfunction in men and may cause headache, high blood pressure, breathing difficulties and other discomforts after taking it. Patients with high blood pressure and heart disease may have an increased risk of developing non-arteritic anterior ischemic optic neuropathy after taking it. Secondly, it is forbidden for those who are allergic to the components of the drug, those who are taking nitrate drugs, and women. And it is forbidden to combine it with nitrate drugs while taking it to avoid causing hypotension. If the erection lasts more than 4 hours after taking the drug and is accompanied by pain, you should consult a doctor immediately. 2. Sildenafil belongs to the cyclic guanosine monophosphate specific phosphodiesterase type 5 inhibitor, after the use of sexual stimulation, resulting in the cavernous body of the vascular smooth muscle relaxation, blood inflow, thus making the penis erect. It is mainly used to treat erectile dysfunction. The drug may cause angina, low blood pressure, heart failure and other discomforts when taken. It is contraindicated for those who are allergic to the components of the drug. It should be used with caution in patients with hypertension of the second degree or higher, heart failure. If any discomfort occurs in the course of taking the drug, you should consult a doctor immediately. 3. As mentioned above, both Sildenafil and Avanafil may cause fluctuation of blood pressure, resulting in symptoms of hypotension or hypertension. Therefore, they are not suitable for patients with high blood pressure. If you need to take medication due to your condition, it is recommended that you decide on the dosage and learn the precautions after a comprehensive assessment of your condition by your doctor.