Methimazole allergy for drug dermatitis, need to stop the drug in time, and then according to the symptoms of drug treatment. 1. Timely discontinuation of medication: first of all, methimazole should be discontinued and caution should be exercised in the use of drugs with similar results. 2. Mild symptoms: local topical glycerine lotion, mometasone furoate cream, etc. for relief, oral antihistamines, such as fexofenadine hydrochloride tablets, loratadine tablets, etc.; if necessary, give a small dose of glucocorticoids. 3. Heavy symptoms: early and adequate use of glucocorticosteroids, prevention of secondary infections, strengthening supportive therapy. When anaphylaxis occurs, glucocorticoid and epinephrine should be applied. The above drugs should not be taken privately to avoid adverse reactions. After methimazole allergy, it is recommended to go to the hospital in time for treatment under the guidance of the doctor.